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Health Testing

Blood Tests You Should Be Doing During Your 40s

Give Zero Team
January 20, 2024

Your 40s are a crucial decade for understanding what's happening in your body. As hormones begin to shift and metabolic changes occur, the right blood tests can provide invaluable insights into your health and help you take proactive steps to feel your best.

Why These Tests Matter

These five essential blood tests can help identify hormonal imbalances, metabolic dysfunction, and inflammation before they become serious health issues. Early detection means better outcomes and more treatment options.

1

Comprehensive Thyroid Panel

Your thyroid function can be affected and worsen weight gain, fatigue and metabolic health. If you are suffering from any of these symptoms you should rule out hypothyroidism or Hashimoto's.

Tests to Include:

  • TSH (Thyroid Stimulating Hormone)

    Primary screening test for thyroid function

  • Free T3 & Free T4

    Active thyroid hormones that affect metabolism

  • Reverse T3

    Can indicate stress or conversion issues

  • Thyroid Antibodies

    Screens for autoimmune thyroid conditions

2

Fasting Insulin and Glucose

This test evaluates your insulin resistance and metabolic function. High insulin levels can indicate prediabetes and metabolic dysfunction. This can lead to fat loss resistance and an increase in inflammation markers.

Why This Matters:

  • Early detection of insulin resistance before diabetes develops
  • Understanding why weight loss might be difficult
  • Identifying metabolic dysfunction that affects energy levels
3

Inflammatory Markers

These are markers of systemic inflammation that are linked to increase in cardiovascular disease and metabolic dysfunction. Include CRP and Omega 3 levels to check for potential chronic inflammation.

CRP (C-Reactive Protein)

Measures general inflammation in the body and cardiovascular risk

Omega-3 Levels

Assesses anti-inflammatory fatty acid status and heart health

4

Full Female Sex Hormone Panel

Check your estradiol, progesterone, testosterone, DHEA-S, FSH - this is key because to assess peri/menopause we need to correlate these levels with your symptoms. Low estrogen can produce insulin resistance, lipid metabolism, cardiovascular health, bone health, muscle building issues.

Hormones to Test:

Estradiol

Primary estrogen hormone

Progesterone

Balances estrogen effects

Testosterone

Affects energy and libido

DHEA-S

Adrenal hormone precursor

FSH

Indicates ovarian function

Important Note:

FSH above 25 is strongly correlated with low estrogen levels. Make sure you check these levels and correlate them with your symptoms for accurate assessment.

5

Homocysteine

High levels of homocysteine indicate inflammation and increased cardiovascular risk. Can signal issues with detoxification and metabolism.

What High Levels May Indicate:

  • Increased cardiovascular disease risk
  • B-vitamin deficiencies (B6, B12, folate)
  • Impaired detoxification pathways
  • Chronic inflammation

Taking Action

Getting these tests is just the first step. The real value comes from understanding your results and working with a healthcare provider who specializes in women's health and hormone optimization.

Remember: optimal ranges may be different from "normal" lab ranges. What matters is how you feel and function, not just whether you fall within the reference range.

Next Steps

  • Discuss these tests with your healthcare provider
  • Consider working with a functional medicine practitioner
  • Track your symptoms alongside your test results
  • Retest periodically to monitor changes

Related Articles

Treatment Options

Hormone Pellets in Perimenopause: What You Need to Know

Understanding treatment options for hormonal symptoms.

Symptoms

20 Symptoms You Didn't Know Were Connected

Surprising signs that could be linked to menopause.

Nutrition

What to Eat When Hormones Go Off Track

Foods that can help reduce symptoms by up to 30%.