Why Give Zero exists
Give Zero (yes, as in 0fs) is here so women can own their hormonal health. Too many discover (peri)menopause without information or support. Too often we've been left wondering, "How come no one told me?!" We wait no more.
Mission
Make sure no woman goes through menopause uninformed or unsupported. Suffering is not a normal part of aging.
Goal
Become the home for menopause. Women's one stop for answers, options, action. Completely personalized by your data.
Promise
Evidence based guidance that puts you in control of your health. We help you understand symptoms, compare treatments and take steps.
The problem we're solving
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85% of women experience perimenopause or menopause symptoms.
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Many hear "you're too young," "it's just menopause," or "your labs are fine."
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Care is fragmented; reliable information and options are hard to find.
What you get with Give Zero
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Personalized guidance based on your symptoms, labs, and wearables.
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Clear options: hormone therapy, non-hormonal medicines, vaginal therapies, sleep and stress strategies, pelvic floor care, nutrition, and exercise.
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Action plans to discuss with your clinician, questions to ask, tests to consider, and micro-steps to try.
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24/7 AI companion to track progress and prepare for appointments.
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Completely personalized, your data powers your plan.
Suffering is not part of aging. It's a signal—and you deserve answers.
Quick answers
What is perimenopause?
Perimenopause is the transition before menopause when hormones fluctuate, often causing hot flashes, sleep changes, brain fog, mood shifts, weight changes, and vaginal dryness.
How does Give Zero help?
We combine your data (symptoms, labs, wearables) with clinically reviewed information to create a personalized action plan and ongoing coaching.
Is this medical care?
Give Zero provides education and support to help you make informed decisions with your clinician.
Who's behind Give Zero?
I'm Pia Mancini, a tech founder who hit perimenopause without a playbook.
I've always had migraines; at 37 they started hitting every couple of weeks—two or three days in the dark, sometimes the ER—until I found the right meds.
With a related family history and an APOE4 risk, brain health became urgent. I didn't know hormones could be involved. I went looking for answers and found a maze. Researching the estrogen–brain connection, I learned women make up two-thirds of Alzheimer's patients. None of my doctors mentioned it. Care is siloed; your OB-GYN doesn't know the brain, and fewer than 20% have any menopause training.
After years of brush-offs—"you're too young," "your labs are fine"—I built Give Zero so women can get informed and own their hormonal health.
I've spent my career building systems that give people agency. Give Zero is the resource I needed: private, personalized, evidence-based guidance, powered by your data and tailored to your reality.
They say if you've met one woman in menopause, you've met one woman. Our experiences are unique. Let's own them. Give Zero is here to help.
Suffering is not part of aging. It's a signal—and you deserve answers.
Pia Mancini — Founder & CEO