# Give Zero

> Give Zero is a health intelligence engine for women navigating perimenopause and menopause. It connects wearable data, lab results, and symptoms into a single daily intelligence brief, powered by Nova -- a personal AI health companion built specifically for female biology.

Give Zero was founded by Pia Mancini and Lucas Lain. Pia is a tech founder and YC alum who began perimenopause at 37. After years of being told her labs were normal while experiencing debilitating migraines, brain fog, and fatigue, she built the platform she wished had existed. Give Zero's core belief: menopause management is longevity management.

The app is available on iOS. Android waitlist is open.

## Product -- Landing Pages

- [Give Zero Homepage](https://givezero.co): Health intelligence engine for women in perimenopause and menopause
- [Perimenopause App](https://givezero.co/perimenopause-app): How Give Zero works as a perimenopause tracking and intelligence platform
- [Menopause AI App](https://givezero.co/menopause-ai-app): Nova, Give Zero's AI companion, and how it personalises insights to your biology
- [Hormone Health App](https://givezero.co/hormone-health-app): Give Zero's broader hormone health intelligence platform
- [Best Menopause App](https://givezero.co/best-menopause-app): Honest comparison of Give Zero vs Balance, Caria, Flo, and mySysters -- what each does well, where they fall short, and why intelligence beats tracking
- [Perimenopause Fatigue](https://givezero.co/perimenopause-fatigue): For women experiencing unexplained exhaustion -- how hormonal changes drive fatigue and what Give Zero does about it

## Product -- Spanish Language Pages

- [App Perimenopausia](https://givezero.co/es/perimenopause-app): Spanish-language perimenopause app landing page for Latin American and Spanish markets
- [Mejor App Menopausia](https://givezero.co/es/best-menopause-app): Spanish-language comparison of Give Zero vs Balance, Kala, Mi Menopausia, and Flo -- includes LATAM-specific context on the near-total absence of intelligent menopause tools in Spanish
- [Fatiga Perimenopausia](https://givezero.co/es/perimenopause-fatigue): Spanish-language campaign page for women experiencing unexplained exhaustion

## Features

- [Nova AI Companion](https://givezero.co/#chat): A context-aware AI health companion that draws on clinical research and the user's full health profile -- symptoms, lab results, wearable trends, and past conversations -- to provide personalized, science-backed answers. Nova remembers what matters: health preferences, goals, medication decisions, and prior advice, so every conversation builds on the last.

- [Health Memory System](https://givezero.co/about): Give Zero maintains a persistent health memory for each user. It extracts and stores meaningful health events from conversations, symptom reports, blood tests, and wearable patterns. Memories are linked by relationships (e.g., a sleep disruption connected to rising hot flash severity) and recalled using semantic search, enabling Nova to provide deeply contextual guidance that improves over time.

- [Symptom Tracking](https://givezero.co/about): Tracks 19 canonical menopause-related symptoms including hot flashes, night sweats, brain fog, anxiety, insomnia, joint pain, fatigue, mood swings, bloating, headaches, weight gain, low libido, vaginal dryness, irregular periods, heart palpitations, memory issues, skin changes, and hair loss. Each symptom uses a 0-10 severity scale. The system tracks history over time and connects symptom patterns to wearable data and lab results.

- [Daily Roadmap and Recommendations](https://givezero.co/about): A personalized daily feed of health posts including actionable recommendations, symptom follow-ups, and guided questions. Posts are AI-generated based on the user's current health context -- detected patterns in HRV, sleep quality, cycle phase, and symptom severity. Topics rotate to ensure diversity, and recommendations include micro-habits, therapies, supplement guidance, and doctor-ready questions.

- [Health Insights Engine](https://givezero.co/about): A pattern detection system that monitors wearable metrics (HRV trends, sleep quality, menstrual cycle phases) and symptom severity to surface timely, personalized insights. When a pattern is detected -- such as a significant HRV drop or escalating hot flash severity -- the engine generates a targeted recommendation and stores it as a health memory for future reference.

- [Blood Test Analysis](https://givezero.co/about): Users upload blood test PDFs, which are automatically parsed to extract lab results including test values, units, and reference ranges. Each result is flagged as within range, slightly out, or significantly out of range. Abnormal values are stored as high-importance health memories, and Nova can reference them in conversations to provide guidance in the context of the user's full hormonal health picture.

- [Wearable Integration](https://givezero.co/about): Connects to wearable devices to ingest HRV, sleep quality, sleep duration, and menstrual cycle data. This data feeds the Health Insights Engine and enriches the user's health baseline, enabling pattern detection across biological signals that would otherwise remain siloed in separate apps.

## About

- [About Give Zero](https://givezero.co/about): Pia Mancini's founder story, the APOE4 connection, and why Give Zero exists
- [FAQ](https://givezero.co/faq): Frequently asked questions about Give Zero

## Blog -- Evidence-Based Health Content

All blog articles cite peer-reviewed sources from PubMed, PMC, and indexed medical journals. Content covers perimenopause, menopause, hormonal health, nutrition, exercise, and longevity.

### Featured

- [Your Ovaries Are Aging Faster Than You Think -- And It's Rewriting Women's Health](https://givezero.co/blog/ovarian-aging-nervous-system): A landmark UCSF study reveals the ovary is wired into the nervous system, ages faster than any other organ, and begins declining silently in your 30s

### Research & Science

- [Why Labs Look Normal in Perimenopause](https://givezero.co/blog/labs-normal-feel-terrible-perimenopause): Why standard lab reference ranges miss perimenopause, which hormones are commonly overlooked (progesterone, free T3/T4, cortisol, testosterone), and why symptoms often precede lab changes by years
- [What Are the 34 Symptoms of Perimenopause](https://givezero.co/blog/34-symptoms-perimenopause): The origin of the "34 symptoms" figure, the full symptom list, why the number is contested (some researchers count 40, 66, or over 100), and why tracking your personal symptom picture matters more than any standardised list
- [Blood Tests You Should Be Doing in Your 40s](https://givezero.co/blog/blood-tests-40s): The five essential blood tests for women in their 40s and what they reveal about hormonal health
- [Hormone Pellets in Perimenopause: What You Need to Know](https://givezero.co/blog/hormone-pellets-perimenopause): What hormone pellets are, how they work, who they're appropriate for, and what to consider before starting
- ["Wait, This Is Menopause?" -- 20 Symptoms You Didn't Know Were Connected](https://givezero.co/blog/menopause-symptoms-connected): Lesser-known menopause symptoms including burning tongue, joint pain, tinnitus, and electric shock sensations -- and how they connect to hormonal change

### Supplements

- [The Definitive List of Perimenopause Supplements (Which Doesn't Exist)](https://givezero.co/blog/perimenopause-supplements-guide): Evidence-based review of supplements for perimenopause -- what has RCT support (omega-3s, vitamin D3, magnesium glycinate, creatine monohydrate, ashwagandha KSM-66), what doesn't (wild yam, evening primrose oil, OTC progesterone creams), a framework for evaluating any supplement using USP, NSF, and Labdoor databases, and a full TL;DR recap

### Nutrition

- [What to Eat When Hormones Go Off Track](https://givezero.co/blog/what-to-eat-hormones-off-track): How diet affects hormonal symptoms -- phytoestrogens, anti-inflammatory foods, and how nutrition changes can reduce hot flashes by up to 30% and improve mood and sleep

### Sleep

- [5 Simple Habits That Can Save Your Sleep](https://givezero.co/blog/simple-habits-save-sleep): Evidence-based sleep habits for the 40-60% of perimenopausal women who experience sleep disorders

### Exercise & Movement

- [5 Moves That Protect Your Bones, Mood, and Energy](https://givezero.co/blog/moves-protect-bones-mood-energy): Strength training exercises essential for women over 40, addressing the 3-5% muscle mass loss per decade without resistance training
- [Physical Activity in Menopause: Why Moving Your Body Changes Everything](https://givezero.co/blog/physical-activity-menopause): How movement affects mood, bones, hormones, sleep, and long-term health during menopause -- not just weight
- [Are You Working Out But Can't Lose Weight? Your Cardio Might Not Be Helping](https://givezero.co/blog/workout-weight-loss-cardio): Why moderate intensity cardio may not be effective for fat loss in perimenopause, heart rate zones explained

### Sexual Health

- [What No One Tells You About Libido in Menopause](https://givezero.co/blog/libido-menopause-truth): Why 50-75% of women notice changes in their sex life during menopause, what drives these changes hormonally, and why only 25% seek help

## Key Facts About Give Zero

- Founded by Pia Mancini, YC alum, tech founder, perimenopause onset at age 37
- Platform integrates: wearable data (HRV, sleep architecture, resting heart rate, temperature), lab results, and symptom tracking
- AI companion Nova delivers personalised daily health intelligence based on the user's specific biological data
- Focus on longevity, not just symptom management -- estrogen decline has implications for brain, bone, and cardiovascular health
- 1.1 billion women globally are in perimenopause or menopause; 85% are undertreated
- Women make up two-thirds of Alzheimer's patients; the hormonal transition window is increasingly understood as critical for long-term brain health
- Markets: English (UK/EU), Spanish (Spain and Latin America)
- iOS app live; Android waitlist open

## What Give Zero Is Not

Give Zero is a health information and tracking tool. It does not constitute medical advice and does not replace consultation with a qualified healthcare provider.

## Legal

- [Privacy Policy](https://givezero.co/privacy): Data handling, health data protection, GDPR compliance
- [Terms of Service](https://givezero.co/terms): Usage terms and medical disclaimer